From Junk DNA to Evolution’s Hidden Engine: Rethinking the Dark Genome

TV Venkateswaran

IMG

The completion of the Human Genome Project in 2003 is one of the greatest achievements in modern science. Its purpose was to generate a reference human genome, a standard map against which all other human genomes could be compared. This first reference genome, named GRCh37 for Genome Reference Consortium Human Build 37, was assembled from DNA taken from several anonymous donors. It was 92% finished. Scientists have continued to improve this map since that time. In 2013, an updated version of GRCh38 corrected many errors and filled many gaps. Most recently, the Telomere-to-Telomere (T2T-CHM13) consortium produced the first truly near-complete sequence of the human genome in 2022, adding in regions that had been unread for almost two decades…read more on NOPR